Anticoagulation Meds 💉

💊 Anticoagulants & Antiplatelets

Includes common medications used for anticoagulation and antiplatelet therapy in hospital settings.
Refer to renal and hepatic considerations when prescribing.

Reference table for anticoagulation therapy

Drug	Dose	Frequency	Route	Notes
Enoxaparin	20-40mg	OD	SC	40mg OD standard dose. 40mg BD if BMI >40 or >120kg. 20mg for low risk or GFR <30.
Tinzaparin	3500-4500iu	OD	SC	VTE prophylaxis <100kg. More useful for outpatient settings.
Aspirin	75-300mg	OD	PO	75mg stent protection. 300mg for MI/CVA.
Clopidogrel	75-600mg	OD	PO
Prasugrel	5-60mg	OD	PO	PCI: 60mg load, 10mg maintenance. 5mg if <60kg. Avoid if prior TIA/stroke.
Rivaroxaban	20mg	OD	PO	GFR 30-49: 15mg. GFR <30: do not use.
Edoxaban	60mg	OD	PO	Cr 15-50 OR <60kg OR inhibitors: 30mg.
Apixaban	2.5-5mg	BD	PO	Use 2.5mg BD if two of: Creat >133, Age >80, Weight <60kg. GFR 15-30: 2.5mg BD.

Dose:20-40mg

Frequency:OD

Notes: 40mg OD standard dose. 40mg BD if BMI >40 or >120kg. 20mg for low risk or GFR <30.

Dose:3500-4500iu

Frequency:OD

Notes: VTE prophylaxis <100kg. More useful for outpatient settings.

Dose:75-300mg

Frequency:OD

Notes: 75mg stent protection. 300mg for MI/CVA.

Dose:75-600mg

Frequency:OD

Dose:5-60mg

Frequency:OD

Notes: PCI: 60mg load, 10mg maintenance. 5mg if <60kg. Avoid if prior TIA/stroke.

Dose:20mg

Frequency:OD

Notes: GFR 30-49: 15mg. GFR <30: do not use.

Dose:60mg

Frequency:OD

Notes: Cr 15-50 OR <60kg OR inhibitors: 30mg.

Dose:2.5-5mg

Frequency:BD

Notes: Use 2.5mg BD if two of: Creat >133, Age >80, Weight <60kg. GFR 15-30: 2.5mg BD.